منابع مشابه
Alcoholic Liver Disease: Introduction
What is Alcoholic Liver Disease? As the name implies, alcoholic liver disease is liver injury attributed to alcohol abuse. The majority of Americans manage to drink alcohol without serious consequences. Research suggests, however, that liver disease may begin to develop after a "threshold" dose of alcohol has been consumed—generally assumed to be four drinks a day (four 12 ounces beers, four gl...
متن کاملAlcoholic liver disease.
Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirrhosis. The exact pathogenesis of alcoholic liver injury is still not clear but...
متن کاملAlcoholic liver disease
During the 1950s and '60s when the debate about the relative contribution of alcohol toxicity and malnutrition to alcohol related liver damage was raging in the United States,' Britain was more interested in other forms of liver disease. As awareness ofthe size of the alcohol problem grew in this country,2 3 research work at the Liver Unit began to reflect the changing situation. Immunology was...
متن کامل[Alcoholic liver disease].
Alcohol has been implicated in the genesis of liver disease for centuries. Significant progress has been made in our understanding of the pathogenesis of ALD. It is now apparent that both the consumption and the metabolism of alcohol promote the production of inflammatory mediators (cytokines) that result in hepatotoxicity and fibrogenesis. With time, this leads to progressively severe liver in...
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ژورنال
عنوان ژورنال: Experimental and Molecular Pathology
سال: 2015
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2015.03.007